Автор: oleg
создано: 20.10.2005 14:00
Mepivacaine Hydrochloride. This product was originally used under the name Scandicaine® for epidural anesthesia in cases of short, local surgical procedures. Mepivacaine has been on the market since 1957. More recently, it was introduced into dental practices under the trade name Scandonest™ 3%. The advantage of this product is that it is available without vasoconstrictor and preservative.
However, the low clearance and the prolonged terminal half–life in neonates, makes Carbocaine less suitable for use in obstetric anaesthesia [5-7].
Moore RG, Thomas J, Triggs EJ, et al: The pharmacokinetics and metabolism of the anilide local anaesthetics in neonates. Eur J Clin Pharmacol 1978; 14: 203-12
6. Brown WU, Bell GC, Lurie AO, Weiss JB, Scanlon JW, Alper MH. Newborn blood levels of lidocaine and mepivacaine in the first postnatal day following maternal epidural anesthesia. Anaesthesiology 1975;42:698-707.
7. Tucker GT, Mather L. Properties, absorption, and disposition of local anesthetic agents. In: Cousins MJ, Bridenbaugh PO, editors. Neural blockade in clinical anesthesia and management of pain.3rd edition Lippincott Raven, 1998:55-95.
|
Re: Скандонест 3% 
Скандонест 3% 
Re: Скандонест 3% 